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Generoso Luca COLUCCI D'AMATO

Insegnamento di CELLULAR AND MOLECULAR NEUROBIOLOGY AND NEUROPATHOLOGY

Corso di laurea magistrale in MOLECULAR BIOTECHNOLOGY

SSD: MED/04

CFU: 4,00

ORE PER UNITÀ DIDATTICA: 32,00

Periodo di Erogazione: Secondo Semestre

Italiano

Lingua insegnamento

INGLESE

English

Teaching language

English

Contents

Understanding the organization, and functions of nervous system, including cells and molecules involved. Understanding the cellular and molecular basis of the main human diseases affecting the CNS.

Textbook and course materials

Basic texts:
-Principles of Neurobiology, Liqun Luo, 2016, Garland Science;
-Principle of Neural Sciences, Kandel ER et al., 2012, McGraw-Hill

Course objectives

The course is designed to describe the structural and functional basis of the organization of the Nervous System, as well as the pathogenetic mechanisms of its main diseases. The course will also describe the main experimental approaches to study neural alterations, including cellular and animal models. Finally, students will be introduced to the main recent advances that have challenged long-standing beliefs in the function of Nervous System and their implications in the mechanisms of diseases will be discussed.

Prerequisites

Knowledge acquired with a Bachelor degree in Biotechnology or in Biology, or equivalent academic degrees.

Teaching methods

Frontal lessons.Moreover, lectures might be also given by invited speakers on selective topics.PowerPoint presentations by students on selective topics.

Assessment methods

Students will be assessed through a combination of oral examination and coursework (i.e. presentation of articles, bibliographic search activity, active interactions with lecturers)

Other information

Supplementary material will be provided during the course by lecturer and invited speakers. The Professor will receive students upon request

Detailed syllabus

-Gross anatomy of Nervous System
- The cells of Nervous System
- Neurotrophic factors
Neurotransmitters
- Stem cells and their potential in regenerative medicine
- Neural plasticity, learning and memory
- Mechanisms of the main diseases (neurodegeneration, autoimmune diseases, gliomas, depression and schizophrenia)

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